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12732 details
Primary information
ID12732
Uniprot IDP01501
DescriptionMelittin (MEL) (MLT) (Allergen Api m 3) (Allergen Api m III) (allergen Api m 4)
OrganismApis mellifera
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Hymenoptera; Apocrita (wasps; ants; and bees); Aculeata; Apoidea (bees); Apidae (bumble bees and honey bees); Apinae (honey bees); Apini; Apis; Apis mellifera (Honeybee)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the melittin family.
Tissue SpecificityExpressed by the venom gland.
Post Translational ModificationNA
FunctionMelittin- Main toxin of bee venom with strong hemolytic activity and antimicrobial activity
Length70
Molecular Weight7
NameNA
SequenceNA
Sequence mapNA
PDB ID1BH1; 2MLT; 2MW6; 3QRX; 6DST; 6O4M;
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseMelittin is an attractive candidate for cancer chemotherapy causing more damage to the tumor cell membranes since its membrane potential is higher and cells are less likely to develop resistance to a