Primary information |
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ID | 12732 |
Uniprot ID | P01501 |
Description | Melittin (MEL) (MLT) (Allergen Api m 3) (Allergen Api m III) (allergen Api m 4) |
Organism | Apis mellifera |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Hymenoptera; Apocrita (wasps; ants; and bees); Aculeata; Apoidea (bees); Apidae (bumble bees and honey bees); Apinae (honey bees); Apini; Apis; Apis mellifera (Honeybee) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the melittin family. |
Tissue Specificity | Expressed by the venom gland. |
Post Translational Modification | NA |
Function | Melittin- Main toxin of bee venom with strong hemolytic activity and antimicrobial activity |
Length | 70 |
Molecular Weight | 7 |
Name | NA |
Sequence | NA |
Sequence map | NA |
PDB ID | 1BH1; 2MLT; 2MW6; 3QRX; 6DST; 6O4M; |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | Melittin is an attractive candidate for cancer chemotherapy causing more damage to the tumor cell membranes since its membrane potential is higher and cells are less likely to develop resistance to a |