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12728 details
Primary information
ID12728
Uniprot IDO93416
DescriptionLeptin (Obesity factor) (Fragment)
OrganismMeleagris gallopavo
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae (turkeys); Meleagridinae; Meleagris; Meleagris gallopavo (Wild turkey)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the leptin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionKey player in the regulation of energy balance and body weight control. Once released into the circulation; has central and peripheral effects by binding LEPR; found in many tissues; which results in the activation of several major signaling pathways.
Length145
Molecular Weight15
NameLeptin
SequencePCQIFQDDTKTLIKTIVTRINDISHTSVSAKQSVTGLDFIPGLHPILSLSKMDQTLAVYQQVLTSLPSQNVLQIANDLENLRDLLHLLAFSKSCSLPQTSGLHKPESLDGVLEALLYSTEVVALSRLQGSLQDILQQLDISPEC
Sequence map3-25
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA