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12693 details
Primary information
ID12693
Uniprot IDP01012
DescriptionOvalbumin (Allergen Gal d II) (Egg albumin) (Plakalbumin) (allergen Gal d 2)
OrganismGallus gallus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae (turkeys); Phasianinae; Gallus; Gallus gallus (Chicken)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the serpin family. Ov-serpin subfamily.
Tissue SpecificityMajor protein of egg white. Expressed in the magnum of the oviduct (at protein level) (PubMed-25436390).
Post Translational ModificationUndergoes proteolytic cleavage first at the canonical P1-P1' site; and then at the P8-P7 site by subtilisin.
FunctionNon-inhibitory serpin. Storage protein of egg white.
Length386
Molecular Weight42
NameOvalbumin
SequenceSIGAASMEFCFDVFKELKVHHANENIFYCPIAIMSALAMVYLGAKDSTRTQINKVVRFDKLPGFGDSIEAQCGTSVNVHSSLRDILNQITKPNDVYSFSLASRLYAEERYPILPEYLQCVKELYRGGLEPINFQTAADQARELINSWVESQTNGIIRNVLQPSSVDSQTAMVLVNAIVFKGLWEKAFKDEDTQAMPFRVTEQESKPVQMMYQIGLFRVASMASEKMKILELPFASGTMSMLVLLPDEVSGLEQLESIINFEKLTEWTSSNVMEERKIKVYLPRMKMEEKYNLTSVLMAMGITDVFSSSANLSGISSAESLKISQAVHAAHAEINEAGREVVGSAEAGVDAASVSEEFRADHPFLFCIKHIATNAVLFFGRCVSP
Sequence map8-26
PDB ID1JTI; 1OVA; 1P1Z; 1P4L; 1UHG; 1VAC; 3C8K; 3CVH; 3P9L; 3P9M; 3PAB; 4HKJ;
DrugpediaNA
ReceptorNA
DomainThe uncleaved signal peptide becomes available for
Pharmaceutical UseNA