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12665 details
Primary information
ID12665
Uniprot IDA4IH36
DescriptionAdipolin (Adipose-derived insulin-sensitizing factor) (Complement C1q tumor necrosis factor-related protein 12)
OrganismXenopus tropicalis
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the adipolin/erythroferrone family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionInsulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue.
Length324
Molecular Weight35
NameAdipolin
SequenceKKERKKGKDPHQFTEPFNVSLSNSEELHETDKLSETPDPGLPDAYTTWLGFVGRTDDGANSKKKCKGKDKKLRGLFGPPGPPGPQGPPGPPGMPGAEVTYEVLLQDFKQMLKEATERRLMSGDIPEHTSELPPIVLPVEDLSPYRRVDEGFHCRLKGQVIVDKKTLVELQNFQMPTAKGSFLRGSGLNLATGRFTASVPGIYQFSAHVHIDHSEIKSKAQLRPRDNVRVLICIESMCHRYTSLEVIAGLESNSKIFTVHVQGLLQLQVGQYTSIFVDNSAGAPITVQNGSDFMGILMGL
Sequence map30-24
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA