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12657 details
Primary information
ID12657
Uniprot IDA1L2K1
DescriptionMeteorin-like protein
OrganismXenopus laevis
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis (African clawed frog)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the meteorin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionHormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance.
Length286
Molecular Weight32
NameMeteorin-like protein
SequenceLYSSDMCNWKGSGLTHEGHTKDVEQVYLRCSEGSVEWLYPTGAMVINLRPNTLTSAYKHLTVCIKPFKDSKGANIYSEKTGELKLVVPDGENNPHKVYCFGLDRGGLYIEATPQQDISRKITGFQYELISQRTLSDLHTVSDPCRPCSDTEVLLAVCISDFVVKGTISAVTNDEELQESLINVTVDKLYRQKSKIFLPKDNGGWEGMIRTPLECGVKTGMGSFLFTGRMHFGEPRLGCTPRYKDFKRIYLEAKKQGLNPCEISTD
Sequence map25-46
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA