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12628 details
Primary information
ID12628
Uniprot IDP12763
DescriptionAlpha-2-HS-glycoprotein (Asialofetuin) (Fetuin-A)
OrganismBos taurus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos (oxen; cattle); Bos taurus (Bovine)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the fetuin family.
Tissue SpecificityLiver and bone.
Post Translational ModificationPhosphorylated by FAM20C in the extracellular medium.
FunctionPromotes endocytosis; possesses opsonic properties and influences the mineral phase of bone. Suggested to have lymphocyte stimulating properties; lipid binding capability and to bind thyroid hormone.
Length359
Molecular Weight38
NameAlpha-2-HS-glycoprotein
SequencePLDPVAGYKEPACDDPDTEQAALAAVDYINKHLPRGYKHTLNQIDSVKVWPRRPTGEVYDIEIDTLETTCHVLDPTPLANCSVRQQTQHAVEGDCDIHVLKQDGQFSVLFTKCDSSPDSAEDVRKLCPDCPLLAPLNDSRVVHAVEVALATFNAESNGSYLQLVEISRAQFVPLPVSVSVEFAVAATDCIAKEVVDPTKCNLLAEKQYGFCKGSVIQKALGGEDVRVTCTLFQTQPVIPQPQPDGAEAEAPSAVPDAAGPTPSAAGPPVASVVVGPSVVAVPLPLHRAHYDLRHTFSGVASVESSSGEAFHVGKTPIVGQPSIPGGPVRLCPGRIRYFKI
Sequence map24-59
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA