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12619 details
Primary information
ID12619
Uniprot IDO62682
DescriptionFibroblast growth factor 8 (FGF-8) (Androgen-induced growth factor) (AIGF) (Heparin-binding growth factor 8) (HBGF-8) (Fragment)
OrganismCanis lupus familiaris
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Canidae (dog; coyote; wolf; fox); Canis; Canis lupus (Gray wolf); Canis lupus familiaris (Dog) (Canis familiaris)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the heparin-binding growth factors family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionPlays an important role in the regulation of embryonic development; cell proliferation; cell differentiation and cell migration. Required for normal brain; eye; ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.
Length82
Molecular Weight9
NameFibroblast growth factor 8
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA