| Primary information |
|---|
| ID | 12606 |
| Uniprot ID | Q6WRH9 |
| Description | Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608) |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | Expressed in bone. Main expression is present in mesenchymal osteochondroprogenitors with fibroblast-like morphology abundant in the regions of active bone modeling and remodeling. |
| Post Translational Modification | N-terminally cleaved to produce a form of around 663 residues. |
| Function | Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons). May be involved in the maintenance of osteochondroprogenitor cells pool |
| Length | 2597 |
| Molecular Weight | 284 |
| Name | Immunoglobulin superfamily member 10 |
| Sequence | PRRCACYVPTEVHCTFRYLTSIPDGIPANVERINLGYNSLTRLTENDFDGLSKLELLMLHSNGIHRVSDKTFSGLQSLQVLKMSYNKVQIIRKDTFYGLGSLVRLHLDHNNIEFINPEAFYGLTSLRLVHLEGNRLTKLHPDTFVSLSYLQIFKTSFIKYLFLSDNFLTSLPKEMVSYMPNLESLYLHGNPWTCDCHLKWLSEWMQGNPDIIKCKKDRSSSSPQQCPLCMNPRISKGRPFAMVPSGAFLCTKPTIDPSLKSKSLVTQEDNGSASTSPQDFIEPFGSLSLNMTDLSGNKADMVCSIQKPSRTSPTAFTEENDYIMLNASFSTNLVCSVDYNHIQPVWQLLALYSDSPLILERKPQLTETPSLSSRYKQVALRPEDIFTSIEADVRADPFWFQQEKIVLQLNRTATTLSTLQIQFSTDAQIALPRAEMRAERLKWTMILMMNNPKLERTVLVGGTIALSCPGKGDPSPHLEWLLADGSKVRAPYVSEDGRILIDKNGKLELQMADSFDAGLYHCISTNDADADVLTYRITVVEPYGESTHDSGVQHTVVTGETLDLPCLSTGVPDASISWILPGNTVFSQPSRDRQILNNGTLRILQVTPKDQGHYQCVAANPSGADFSSFKVSVQKKGQRMVEHDREAGGSGLGEPNSSVSLKQPASLKLSASALTGSEAGKQVSGVHRKNKHRDLIHRRRGDSTLRRFREHRRQLPLSARRIDPQRWAALLEKAKKNSVPKKQENTTVKPVPLAVPLVELTDEEKDASGMIPPDEEFMVLKTKASGVPGRSPTADSGPVNHGFMTSIASGTEVSTVNPQTLQSEHLPDFKLFSVTNGTAVTKSMNPSIASKIEDTTNQNPIIIFPSVAEIRDSAQAGRASSQSAHPVTGGNMATYGHTNTYSSFTSKASTVLQPINPTESYGPQIPITGVSRPSSSDISSHTTADPSFSSHPSGSHTTASSLFHIPRNNNTGNFPLSRHLGRERTIWSRGRVKNPHRTPVLRRHRHRTVRPAIKGPANKNVSQVPATEYPGMCHTCPSAEGLTVATAALSVPSSSHSALPKTNNVGVIAEESTTVVKKPLLLFKDKQNVDIEIITTTTKYSGGESNHVIPTEASMTSAPTSVSLGKSPVDNSGHLSMPGTIQTGKDSVETTPLPSPLSTPSIPTSTKFSKRKTPLHQIFVNNQKKEGMLKNPYQFGLQKNPAAKLPKIAPLLPTGQSSPSDSTTLLTSPPPALSTTMAATQNKGTEVVSGARSLSAGKKQPFTNSSPVLPSTISKRSNTLNFLSTETPTVTSPTATASVIMSETQRTRSKEAKDQIKGPRKNRNNANTTPRQVSGYSAYSALTTADTPLAFSHSPRQDDGGNVSAVAYHSTTSLLAITELFEKYTQTLGNTTALETTLLSKSQESTTVKRASDTPPPLLSSGAPPVPTPSPPPFTKGVVTDSKVTSAFQMTSNRVVTIYESSRHNTDLQQPSAEASPNPEIITGTTDSPSNLFPSTSVPALRVDKPQNSKWKPSPWPEHKYQLKSYSETIEKGKRPAVSMSPHLSLPEASTHASHWNTQKHAEKSVFDKKPGQNPTSKHLPYVSLPKTLLKKPRIIGGKAASFTVPANSDVFLPCEAVGDPLPIIHWTRVSSGLEISQGTQKSRFHVLPNGTLSIQRVSIQDRGQYLCSAFNPLGVDHFHVSLSVVFYPARILDRHVKEITVHFGSTVELKCRVEGMPRPTVSWILANQTVVSETAKGSRKVWVTPDGTLIIYNLSLYDRGFYKCVASNPSGQDSLLVKIQVITAPPVIIEQKRQAIVGVLGGSLKLPCTAKGTPQPSVHWVLYDGTELKPLQLTHSRFFLYPNGTLYIRSIAPSVRGTYECIATSSSGSERRVVILTVEEGETIPRIETASQKWTEVNLGEKLLLNCSATGDPKPRIIWRLPSKAVIDQWHRMGSRIHVYPNGSLVVGSVTEKDAGDYLCVARNKMGDDLVLMHVRLRLTPAKIEQKQYFKKQVLHGKDFQVDCKASGSPVPEVSWSLPDGTVLNNVAQADDSGYRTKRYTLFHNGTLYFNNVGMAEEGDYICSAQNTLGKDEMKVHLTVLTAIPRIRQSYKTTMRLRAGETAVLDCEVTGEPKPNVFWLLPSNNVISFSNDRFTFHANRTLSIHKVKPLDSGDYVCVAQNPSGDDTKTYKLDIVSKPPLINGLYANKTVIKATAIRHSKKYFDCRADGIPSSQVTWIMPGNIFLPAPYFGSRVTVHPNGTLEMRNIRLSDSADFTCVVRSEGGESVLVVQLEVLEMLRRPTFRNPFNEKVIAQAGKPVALNCSVDGNPPPEITWILPDGTQFANRPHNSPYLMAGNGSLILYKATRNKSGKYRCAARNKVGYIEKLILLEIGQKPVILTYEPGMVKSVSGEPLSLHCVSDGIPKPNVKWTTPGGHVIDRPQVDGKYILHENGTLVIKATTAHDQGNYICRAQNSVGQAVISVSVMVVAYPPRIINYLPRNMLRRTGEAMQLHCVALGIPKPKVTWETPRHSLLSKATARKPHRSEMLHPQGTLVIQNLQTSDSGVYKCRAQNLLGTDYATTYIQVL |
| Sequence map | 72-17 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
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