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12596 details
Primary information
ID12596
Uniprot IDQ7TQA1
DescriptionImmunoglobulin superfamily member 1 (IgSF1) (Inhibin-binding protein) (InhBP)
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular Location[Isoform 1]- Membrane
Developmental StageExpressed at embryonic day (E) 12.5 in embryo.
SimilarityNA
Tissue SpecificityNA
Post Translational ModificationNA
FunctionSeems to be a coreceptor in inhibin signaling; but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription.
Length1317
Molecular Weight147
NameImmunoglobulin superfamily member 1
SequenceLAVESQPELWIESNYPQAPWENITLWCKSPSRVSSKFLLLKDNSQMTWIRPPYKTFQVSFFIGALTESNTGLYRCCYWKEKGWSKPSKILELEAPGQLPKPIFWIQAETPPLPGCNVNIFCHGWLQDLVFMLFKEGYTEPVDYQVPTGTMAIFSIDNLAPENEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPILAPGESLSLRCQGPIYGMTFALMRLEDLKKSFYHKKPIKNEAYFYFQDLKIQDTGHYLCFYYDGSYRGSLLSDILKIWVTDTFPKTWLLVQPSPVIQMGQNVSLRCGGLMDGVGLALYKKGEEKPLQFLDASSNTGNNSFFLKNVTYRDAGIYSCHYYLTWKTSIKMATYNTVELMVVAWPSSVFKVGKTITLQCRVSHPVLEFSLEWEERTTFQKFSVDGDFLITDIEGQGTGTYSCSYRIEAHPNTWSHRSKPLKLVGPAGFLTWNSILNEAVRVSLTMQLASLLLLVVWIRWKCRRLRLREAWLLGTAQGVAMLFILMALLCCGLCNGALTEEIEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTHSHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVISASLPIRGQELQIRCKGWLEGLGFALYKKGEQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEMQPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGSRVTFNCSTSHEHMSFILYKDGNEIASSDLAWGNPGGSTAHFLIISVGIGDGGNYSCRYYDFSIWSEPSNPVELVVTEFYPKPTLLAQPGPVVLPGKNVTLRCQGIFQGMRFALLQEGTHTPLQFQSTSGTSADFLLHTVGAQDFGNYSCVYYETTMSNRGSSLSTPLMIWVTDTFPRPWLSAEPSSVVTMGQNVTLWCQGPVRGVGYILHKEGEATSMQLWGSTSNEGAFPIINISGASIGRYSCCYHPDWMSPIKIQPSNTLELIVTGLLPKPSLLVQPGPMVAPGENVTLQCQGELPDSTFVLLKEGTRQPLEQQRPSGYRADFWMPVVRDQDSGVYSCVYYLDSAPLVASNHSNSLEIWVTDKPPKPSLSAWPSTIFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSEDGDFVIDNLEGKGIGNYSCSYRLQAYPDIWSEPSDTLELVGAAGPVAQECTVGNIVRSTLIVVVVVALGIVLAVEWKKWPRLRTRGSETDGRDQTVVLEECNQEGEPGTTTNSPSSASQEVSVELTVPI
Sequence map42-57
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA