Detailed description page of Hmrbase2

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12551 details
Primary information
ID12551
Uniprot IDP08494
DescriptionMatrix Gla protein (MGP)
OrganismRattus norvegicus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the osteocalcin/matrix Gla protein family.
Tissue SpecificityNA
Post Translational ModificationRequires vitamin K-dependent gamma-carboxylation for its function.
FunctionAssociates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
Length103
Molecular Weight12
NameMatrix Gla protein
SequenceESHESMESYEVSPFTTRRNANTFISPQQRWHAKAQERVRELNKPAQEINREACDDYKLCERYALIYGYNAAYNRYFRQRRGAK
Sequence map21-43
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA