| Primary information |
|---|
| ID | 12500 |
| Uniprot ID | Q8R1L8 |
| Description | Angiopoietin-like protein 8 (Betatrophin) (Lipasin) (Refeeding-induced fat and liver protein) |
| Organism | Mus musculus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse) |
| Subcellular Location | Secreted |
| Developmental Stage | Expressed during adipogenesis. |
| Similarity | Belongs to the ANGPTL8 family. |
| Tissue Specificity | Expressed in liver and fat. Enriched in white and brown adipose tissues. |
| Post Translational Modification | Proteolytically cleaved at the N-terminus. |
| Function | Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels |
| Length | 198 |
| Molecular Weight | 22 |
| Name | Angiopoietin-like protein 8 |
| Sequence | RPAPVAPLGGPEPAQYEELTLLFHGALQLGQALNGVYRATEARLTEAGHSLGLYDRALEFLGTEVRQGQDATQELRTSLSEIQVEEDALHLRAEATARSLGEVARAQQALRDTVRRLQVQLRGAWLGQAHQEFETLKARADKQSHLLWALTGHVQRQQREMAEQQQWLRQIQQRLHTAALPA |
| Sequence map | 19-18 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|