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12327 details
Primary information
ID12327
Uniprot IDQ91653
DescriptionCorticotropin-releasing factor-binding protein (CRF-BP) (CRF-binding protein) (Corticotropin-releasing hormone-binding protein) (CRH-BP)
OrganismXenopus laevis
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis (African clawed frog)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the CRF-binding protein family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionBinds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Length321
Molecular Weight36
NameCorticotropin-releasing factor-binding protein
SequenceSRYIQMREAAEDALFLLNSDFKRELSEGQIYRRSLRCIDMLSIEGQFTFQADRPQLHCALFLIGEPEEFIIIEYNFVNIDCIGGDILKVFDGWIIKGEKFPSSLDHPLSTMERYTDICEDGDVGSITRSSQNVAMIFFRVQQPGHGFTLTIRKIPNLFPCNVISQSMNGRFTMITPHQHRNCSFSIIYPVVIKIFDLTLGHFNELQLKKPPPKGCGDAGDFVELLGGAGLDPSKMFPLADLCHSFHGSAQMKIGCDNTVVRMVSSGNFINRVTFEYNQLDRQLEKKQGNSVEEACFPSD
Sequence map27-21
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA