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12319 details
Primary information
ID12319
Uniprot IDO77248
DescriptionApolipophorin-3 (Apolipophorin-III) (ApoLp-III)
OrganismSpodoptera litura
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Amphiesmenoptera; Lepidoptera (butterflies and moths); Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Noctuoidea; Noctuidae (owlet moths); Amphipyrinae; Spodoptera; Spodoptera litura (Asian cotton leafworm)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insect apolipophorin-3 family.
Tissue SpecificityExpressed in fat body and secreted in hemolymph. Also expressed in ovary and testis at lower levels.
Post Translational ModificationNA
FunctionAssists in the loading of diacylglycerol; generated from triacylglycerol stores in the fat body through the action of adipokinetic hormone; into lipophorin; the hemolymph lipoprotein. It increases the lipid carrying capacity of lipophorin by covering the expanding hydrophobic surface resulting from diacylglycerol uptake. It thus plays a critical role in the transport of lipids during flight in several species of insects.
Length188
Molecular Weight20
NameApolipophorin-3
SequenceAPPANTLLQDIEKHAAEIHKTFSEQLNSIANSKNTQEVNKAIKDGSDSVLQQLSALSSSLQSAMTDANAKAKTALEQARQNLEKTAEDLRKSHPDVERQAGELRTKLQAAVQNTAQEVQKLAKEVASNVEETNEKLAPKLKEAYENFSKHVEEVQKKVHEAASKQ
Sequence map26-08
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA