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12298 details
Primary information
ID12298
Uniprot IDP04276
DescriptionVitamin D-binding protein (DBP) (VDB) (Gc-globulin) (Group-specific component)
OrganismRattus norvegicus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the ALB/AFP/VDB family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionInvolved in vitamin D transport and storage; scavenging of extracellular G-actin; enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Length476
Molecular Weight53
NameVitamin D-binding protein
SequenceERGRDYEKDKVCQELSTLGKDDFRSLSLILYSRKFPSSTFEQVSQLVKEVVSLTEECCAEGADPNCYDTRTSELSIKSCESDAPFPVHPGTSECCTKEGLERKLCMAALSHQPQEFPAYVEPTNDEICEAFRKDPKGFADQFLFEYSSNYGQAPLPLLVGYTKSYLSMVGSCCTSAKPTVCFLKERLQMKQLLLLTTMSNRVCSQYAAYGKEKSRMSHLIKLAQKVPTANLEDVLPLAEDLTEILSRCCKSTSEDCMARELPEHTLKICGNLSKKNSKFEECCYETTPMGIFMCSYFMPTAEPLQLPAIKLPTSKDLCGQSATQAMDQYTFELSRRTQVPEVFLSKVLDTTLKTLRECCDTQDSVSCFSTQSPLMKRQLTSFIEKGQEMCADYSENTFTEYKKKLAERLRTKMPNASPEELADMVAKHSDFASKCCSINSPPRYCSSQIDAEMRDILQS
Sequence map24-56
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA