Detailed description page of Hmrbase2

This page displays user query in tabular form.

12277 details
Primary information
ID12277
Uniprot IDQ9JHB3
DescriptionMetalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the protease inhibitor I35 (TIMP) family.
Tissue SpecificityExpressed in brain; heart; ovary and skeletal muscle.
Post Translational ModificationNA
FunctionComplexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Length224
Molecular Weight25
NameMetalloproteinase inhibitor 4
SequenceSCAPAHPQQHFCHSALVIRAKISSEKVVPASKDPADTQKLIRYEIKQIKMFKGFEKAKDIQYVYTPFDSSLCGVKLETNSHKQYLLTGQILSDGKVFIHLCNYIEPWEDLSLVQRESLNHHYHQNCGCQITTCYAVPCTISAPNECLWTDWLLERKLYGYQAQHYVCMKHVDGICSWYRGHLHLRKEYVDIIQP
Sequence map33-44
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA