Detailed description page of Hmrbase2

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12266 details
Primary information
ID12266
Uniprot IDD9IX97
DescriptionNatriuretic peptide Na-NP
OrganismNaja atra
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Lepidosauria (lepidosaurs); Squamata (squamates); Bifurcata (split-tongued squamates); Unidentata; Episquamata; Toxicofera; Serpentes (snakes); Colubroidea; Elapidae; Elapinae; Naja; Naja atra (Chinese cobra)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the natriuretic peptide family.
Tissue SpecificityExpressed by the venom gland.
Post Translational ModificationNA
FunctionNatriuretic peptide that dose-dependently induces the rapid relaxation of rat aortic strips phenylephrine-precontracted. Acts by stimulating cGMP production in a dose-dependent manner (by probably activating NPR1 and/or NPR2). May also show potent hypotensive effects.
Length165
Molecular Weight17
NameNA
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA