| Primary information |
|---|
| ID | 12261 |
| Uniprot ID | A0EQL2 |
| Description | Sex hormone-binding globulin (SHBG) |
| Organism | Crocuta crocuta |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Feliformia; Hyaenidae (hyaenas); Crocuta; Crocuta crocuta (Spotted hyena) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Functions as an androgen transport protein; but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone; testosterone; and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. |
| Length | 393 |
| Molecular Weight | 42 |
| Name | Sex hormone-binding globulin |
| Sequence | IQDPPAVHLSSASGQGPVTIMTFDFTKMRKTSSSFELRTWDPEGVILYGDTDPHEDWFMLGLRGGRPEIQIHNHVARLTVGAGPRLDDGKWHQVEVKVLGDLLLLTVDGEEVLCLKQVFGPLASRPQPVVRIAVGGLPFPPSSLRLPLVPALDGCVRRGSWLDHQAQTSVSALSGSPRSCGVESQPGSFFPPGAHAEFSLQDLPQPHAEPWAFSLDLGLQLAAGSGHLLALGTPENPPRLSLQLQDQKVVLSSAWGPQLHLPLVLGAPLQLKLAASGVTLSQGPETEILALPLSDPGSLLNLWVQPHARLFLGALPGEAASASFCLDGLWAQGQKLDMDRALNRSQNIWTHSCPQSLGNDTDTTH |
| Sequence map | 34-33 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|