Primary information |
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ID | 12245 |
Uniprot ID | P05543 |
Description | Thyroxine-binding globulin (Serpin A7) (T4-binding globulin) |
Organism | Homo sapiens |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the serpin family. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Post Translational Modification | NA |
Function | Major thyroid hormone transport protein in serum. |
Length | 415 |
Molecular Weight | 46 |
Name | Thyroxine-binding globulin |
Sequence | SPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA |
Sequence map | 27-55 |
PDB ID | 2CEO; 2RIV; 2RIW; 2XN3; 2XN5; 2XN6; 2XN7; 4X30; 4YIA; |
Drugpedia | DB01629;DB11100;DB08886;DB00023;DB00636;DB00286;DB |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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