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12215 details
Primary information
ID12215
Uniprot IDP07759
DescriptionSerine protease inhibitor A3K (Serpin A3K) (Contrapsin) (SPI-2)
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the serpin family.
Tissue SpecificityExpressed in liver and secreted in plasma.
Post Translational ModificationNA
FunctionContrapsin inhibits trypsin-like proteases.
Length418
Molecular Weight46
NameSerine protease inhibitor A3K
SequencePDGTKEMDIVFHEHQDNGTQDDSLTLASVNTDFAFSLYKKLALKNPDTNIVFSPLSISAALALVSLGAKGKTMEEILEGLKFNLTETPEADIHQGFGNLLQSLSQPEDQDQINIGNAMFIEKDLQILAEFHEKTRALYQTEAFTADFQQPTEAKNLINDYVSNQTQGMIKELISELDERTLMVLVNYIYFKGKWKISFDPQDTFESEFYLDEKRSVKVPMMKMKLLTTRHFRDEELSCSVLELKYTGNASALLILPDQGRMQQVEASLQPETLRKWRKTLFPSQIEELNLPKFSIASNYRLEEDVLPEMGIKEVFTEQADLSGITETKKLSVSQVVHKAVLDVAETGTEAAAATGVIGGIRKAILPAVHFNRPFLFVIYHTSAQSILFMAKVNNPK
Sequence map28-58
PDB IDNA
DrugpediaNA
ReceptorNA
DomainThe reactive center loop (RCL) extends out from th
Pharmaceutical UseNA