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12203 details
Primary information
ID12203
Uniprot IDP0DUS4
DescriptionU-limacoditoxin(1)-Dv5 (U-LCTX(1)-Dv5) (Vulnericin)
OrganismDoratifera vulnerans
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Amphiesmenoptera; Lepidoptera (butterflies and moths); Glossata; Neolepidoptera; Heteroneura; Ditrysia; Apoditrysia; Zygaenoidea; Limacodidae (slug caterpillar moths); Doratifera; Doratifera vulnerans (Mottled cup moth)
Subcellular LocationSecreted
Developmental StageOnly secreted by caterpillars. Adult moth do not have spines.
SimilarityBelongs to the limacoditoxin-1 (ACP-like) family.
Tissue SpecificityExpressed by the spine venom secretory cell. The spine is a cuticular structure containing at its base a single large nucleated venom secretory cell; as well as a central venom reservoir extending thr
Post Translational ModificationNA
FunctionProbable toxin. Does not show activity on the ACP receptor (ACPR) from the mosquito A.aegypti; on receptors of the closely related neuropeptides adipokinetic hormone and corazonin. In vivo; does not reveal any observable effects when injected into crickets (A.domesticus). Does not induce increase in intracellular calcium in mouse DRG neurons; suggesting that it does not induce pain.
Length36
Molecular Weight4
NameNA
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA