Detailed description page of Hmrbase2

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12197 details
Primary information
ID12197
Uniprot IDP52823
DescriptionStanniocalcin-1 (STC-1)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the stanniocalcin family.
Tissue SpecificityExpressed in most tissues; with the highest levels in ovary; prostate; heart; kidney and thyroid. In the kidney; expression is confined to the nephron; specifically in the distal convoluted tubule and
Post Translational ModificationNA
FunctionStimulates renal phosphate reabsorption; and could therefore prevent hypercalcemia.
Length247
Molecular Weight27
NameStanniocalcin-1
SequenceAAQNSAEVVRCLNSALQVGCGAFACLENSTCDTDGMYDICKSFLYSAAKFDTQGKAFVKESLKCIANGVTSKVFLAIRRCSTFQRMIAEVQEECYSKLNVCSIAKRNPEAITEVVQLPNHFSNRYYNRLVRSLLECDEDTVSTIRDSLMEKIGPNMASLFHILQTDHCAQTHPRADFNRRRTNEPQKLKVLLRNLRGEEDSPSHIKRTSHESA
Sequence map38-07
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA