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12109 details
Primary information
ID12109
Uniprot IDQ99P87
DescriptionResistin (Adipose tissue-specific secretory factor) (ADSF) (Adipose-specific cysteine-rich secreted protein A12-alpha) (Cysteine-rich secreted protein FIZZ3)
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the resistin/FIZZ family.
Tissue SpecificityExpressed in white but not brown adipose tissue in a variety of organs.
Post Translational ModificationNA
FunctionHormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.
Length114
Molecular Weight12
NameResistin (Adipose tissue-specific secretory factor) (ADSF) (Adipose-specific cysteine-rich secreted
SequenceSSMPLCPIDEAIDKKIKQDFNSLFPNAIKNIGLNCWTVSSRGKLASCPEGTAVLSCSCGSACGSWDIREEKVCHCQCARIDWTAARCCKLQVAS
Sequence map94
PDB ID1RFX; 1RGX;
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA