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12075 details
Primary information
ID12075
Uniprot IDQ02816
DescriptionInsulin-like growth factor II (IGF-II) (Erythrotropin)
OrganismOncorhynchus mykiss
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Protacanthopterygii; Salmoniformes (salmons and trouts); Salmonidae (salmonids); Salmoninae (trouts; salmons & chars); Oncorhynchus; Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insulin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionThe insulin-like growth factors; isolated from plasma; are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for integrin which is required for IGF2 signaling.
Length214
Molecular Weight24
NameInsulin-like growth factor II (IGF-II) (Erythrotropin)
SequenceEVASAETLCGGELVDALQFVCEDRGFYFSRPTSRSNSRRSQNRGIVEECCFRSCDLNLLEQYCAKPAKSE
Sequence map70
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA