Detailed description page of Hmrbase2

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12074 details
Primary information
ID12074
Uniprot IDQ90WW4
DescriptionInsulin-like growth factor II-A (IGF-II-A) (Insulin-like growth factor 2-A) (xIGF-2)
OrganismXenopus laevis
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis (African clawed frog)
Subcellular LocationSecreted
Developmental StageExpressed both maternally and zygotically. Expressed in the dorsal midline during gastrulation and neurulation.
SimilarityBelongs to the insulin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionThe insulin-like growth factors; isolated from plasma; are structurally and functionally related to insulin but have a much higher growth-promoting activity. Promotes anterior neural development
Length217
Molecular Weight24
NameInsulin-like growth factor II-A (IGF-II-A) (Insulin-like growth factor 2-A) (xIGF-2)
SequenceYRATETLCGGELVDTLQFVCGDRGFYFSTNNGRSNRRPNRGIVDVCCFKSCDLELLETYCAKPTKNE
Sequence map67
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA