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11956 details
Primary information
ID11956
Uniprot IDQ6INW9
DescriptionInsulin-like growth factor II-B (IGF-II-B) (Insulin-like growth factor 2-B)
OrganismXenopus laevis
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis (African clawed frog)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insulin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionThe insulin-like growth factors; isolated from plasma; are structurally and functionally related to insulin but have a much higher growth-promoting activity. Promotes anterior neural development. Acts as a ligand for integrin which is required for IGF2 signaling.
Length217
Molecular Weight25
NameInsulin-like growth factor II-B (IGF-II-B) (Insulin-like growth factor 2-B)
SequenceYRPTETLCGGELVDTLQFVCGDRGFYFSTNNGRSNRRSNRGIVEECCFRSCDLELLETYCAKPSKNE
Sequence map67
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA