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11950 details
Primary information
ID11950
Uniprot IDQ9MYV1
DescriptionCalcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I)
OrganismCanis lupus familiaris
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Canidae (dog; coyote; wolf; fox); Canis; Canis lupus (Gray wolf); Canis lupus familiaris (Dog) (Canis familiaris)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the calcitonin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionCGRP induces vasodilation. It dilates a variety of vessels including the coronary; cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
Length128
Molecular Weight13
NameCalcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I)
SequenceSCNTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSEAF
Sequence map37
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA