Detailed description page of Hmrbase2

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11918 details
Primary information
ID11918
Uniprot IDP0DMC2
DescriptionApelin receptor early endogenous ligand (Protein Elabela) (ELA) (Protein Toddler)
OrganismDanio rerio
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Otomorpha; Ostariophysi; Otophysi; Cypriniphysae; Cypriniformes (carps and others); Cyprinoidei; Danionidae; Danioninae; Danio; Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular LocationSecreted
Developmental StageExpressed from the mid-blastula transition (MBT) to 3 days post-fertilization (dpf) (PubMed-24316148). Ubiquitously expressed in dividing cells of the blastoderm before becoming restricted after gastr
SimilarityBelongs to the Elabela/Toddler family.
Tissue SpecificityExpressed ubiquitously during late blastula and gastrula stages and becomes restricted to the lateral mesoderm; endoderm; and anterior and posterior notochord after gastrulation (PubMed-24407481).
Post Translational ModificationNA
FunctionEndogenous ligand for the apelin receptor (aplnra and/or aplnrb)
Length58
Molecular Weight7
NameApelin receptor early endogenous ligand (Protein Elabela) (ELA) (Protein Toddler)
SequenceDKHGTKHDFLNLRRKYRRHNCPKKRCLPLHSRVPFP
Sequence map37
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA