Detailed description page of Hmrbase2

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11901 details
Primary information
ID11901
Uniprot IDQ801Y3
DescriptionHepcidin-1
OrganismSalmo salar
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Protacanthopterygii; Salmoniformes (salmons and trouts); Salmonidae (salmonids); Salmoninae (trouts; salmons & chars); Salmo; Salmo salar (Atlantic salmon)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the hepcidin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionSeems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity.
Length86
Molecular Weight9
NameHepcidin-1
SequenceQIHLSLCGLCCNCCHNIGCGFCCKF
Sequence map86
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA