Detailed description page of Hmrbase2

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11898 details
Primary information
ID11898
Uniprot IDP82951
DescriptionHepcidin
OrganismMorone chrysops x Morone saxatilis
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Neoteleostei; Eurypterygia; Ctenosquamata; Acanthomorphata; Euacanthomorphacea; Percomorphaceae; Eupercaria; Eupercaria incertae sedis; Moronidae (temperate basses); Morone; Morone chrysops x Morone saxatilis (White bass x Strip
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the hepcidin family.
Tissue SpecificityPredominantly expressed in liver.
Post Translational ModificationNA
FunctionSeems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages.
Length85
Molecular Weight9
NameHepcidin
SequenceGCRFCCNCCPNMSGCGVCCRF
Sequence map21
PDB ID1S6W;
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA