Primary information |
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ID | 11878 |
Uniprot ID | Q7T273 |
Description | Hepcidin-2 |
Organism | Danio rerio |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Otomorpha; Ostariophysi; Otophysi; Cypriniphysae; Cypriniformes (carps and others); Cyprinoidei; Danionidae; Danioninae; Danio; Danio rerio (Zebrafish) (Brachydanio rerio) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the hepcidin family. |
Tissue Specificity | NA |
Post Translational Modification | NA |
Function | Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity. |
Length | 91 |
Molecular Weight | 10 |
Name | Hepcidin-2 |
Sequence | QSHLSLCRFCCKCCRNKGCGYCCKF |
Sequence map | 25 |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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