| Primary information |
|---|
| ID | 11869 |
| Uniprot ID | P83628 |
| Description | Insulin-like growth factor-binding protein 2 (IBP-2) (IGF-binding protein 2) (IGFBP-2) (Fragment) |
| Organism | Oncorhynchus tshawytscha |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Protacanthopterygii; Salmoniformes (salmons and trouts); Salmonidae (salmonids); Salmoninae (trouts; salmons & chars); Oncorhynchus; Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | NA |
| Post Translational Modification | N-glycosylated. |
| Function | Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. |
| Length | 20 |
| Molecular Weight | 2 |
| Name | Insulin-like growth factor-binding protein 2 (IBP-2) (IGF-binding protein 2) (IGFBP-2) (Fragment) |
| Sequence | DLVFYCPKCTAERQTACPKL |
| Sequence map | 20 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | The C-terminus is required for IGF-binding and gro |
| Pharmaceutical Use | NA
|