| Primary information |
|---|
| ID | 11868 |
| Uniprot ID | A1Z0M0 |
| Description | Hepcidin |
| Organism | Larimichthys crocea |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Neoteleostei; Eurypterygia; Ctenosquamata; Acanthomorphata; Euacanthomorphacea; Percomorphaceae; Eupercaria; Eupercaria incertae sedis; Sciaenidae (drums); Larimichthys; Larimichthys crocea (Large yellow croaker) (Pseudosciaena |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the hepcidin family. |
| Tissue Specificity | Expressed in all tissues tested; with highest levels of expression in kidney and lowest levels in liver. Intra-peritoneal injection of lipopolysaccharide results in increased expression in heart; sple |
| Post Translational Modification | NA |
| Function | Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. |
| Length | 85 |
| Molecular Weight | 9 |
| Name | Hepcidin |
| Sequence | RCRFCCRCCPRMRGCGICCRF |
| Sequence map | 21 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|