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11843 details
Primary information
ID11843
Uniprot IDP10092
DescriptionCalcitonin gene-related peptide 2 (Beta-type CGRP) (Beta-CGRP) (Calcitonin gene-related peptide II) (CGRP-II)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the calcitonin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionCGRP induces vasodilation. It dilates a variety of vessels including the coronary; cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
Length127
Molecular Weight13
NameCalcitonin gene-related peptide 2 (Beta-type CGRP) (Beta-CGRP) (Calcitonin gene-related peptide II)
SequenceACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAF
Sequence map37
PDB IDNA
DrugpediaDB14040;DB14041;DB14042;DB12228;
ReceptorP30988; Q16602
DomainNA
Pharmaceutical UseNA