Detailed description page of Hmrbase2

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11840 details
Primary information
ID11840
Uniprot IDQ32KM8
DescriptionAugurin
OrganismBos taurus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos (oxen; cattle); Bos taurus (Bovine)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the augurin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionProbable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest; RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.
Length147
Molecular Weight17
NameAugurin
SequenceMANSSARPAFLVMTALALLLLLCVGPGGISG
Sequence map61
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA