| Primary information |
|---|
| ID | 11826 |
| Uniprot ID | P14138 |
| Description | Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3) |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the endothelin/sarafotoxin family. |
| Tissue Specificity | Expressed in trophoblasts and placental stem villi vessels; but not in cultured placental smooth muscle cells. |
| Post Translational Modification | NA |
| Function | Endothelins are endothelium-derived vasoconstrictor peptides. |
| Length | 238 |
| Molecular Weight | 25 |
| Name | Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3) |
| Sequence | CTCFTYKDKECVYYCHLDIIW |
| Sequence map | 21 |
| PDB ID | 6IGK; |
| Drugpedia | NA |
| Receptor | P25101; P24530 |
| Domain | NA |
| Pharmaceutical Use | NA
|