| Primary information |
|---|
| ID | 11821 |
| Uniprot ID | Q8WRC7 |
| Description | Cardioactive peptide (Cardioacceleratory peptide 2a) (Crustacean cardioactive peptide) (CCAP) |
| Organism | Manduca sexta |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Amphiesmenoptera; Lepidoptera (butterflies and moths); Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Bombycoidea (hawk-moths); Sphingidae (hawkmoths); Sphinginae (small-eyed sphinx moth); Sphingini; Manduca; Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | Abdominal perivisceral organ; major neurohemal release site. Expressed in 116 neurons in post-embryonic central nervous system. Nine pairs of cells are observed in the brain; 4.5 pairs in the subesoph |
| Post Translational Modification | NA |
| Function | Cardioregulatory neurohormone that increases heart beat rate during adult wing inflation; has no effect on beat amplitude. The effect of CCAP is both ino- and chronotropic. |
| Length | 125 |
| Molecular Weight | 14 |
| Name | Cardioactive peptide (Cardioacceleratory peptide 2a) (Crustacean cardioactive peptide) (CCAP) |
| Sequence | PFCNAFTGC |
| Sequence map | 9 |
| PDB ID | 1V46; |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|