| Primary information |
|---|
| ID | 11820 |
| Uniprot ID | P06881 |
| Description | Calcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I) |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the calcitonin family. |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | CGRP induces vasodilation. It dilates a variety of vessels including the coronary; cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. |
| Length | 128 |
| Molecular Weight | 13 |
| Name | Calcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I) |
| Sequence | ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF |
| Sequence map | 37 |
| PDB ID | 1LS7; 6E3Y; 7KNU; |
| Drugpedia | DB14040;DB14041;DB14042;DB04869;DB12228; |
| Receptor | Q16602 |
| Domain | NA |
| Pharmaceutical Use | NA
|