Detailed description page of Hmrbase2

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11814 details
Primary information
ID11814
Uniprot IDP20800
DescriptionEndothelin-2 (ET-2) (Preproendothelin-2) (PPET2)
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the endothelin/sarafotoxin family.
Tissue SpecificityExpressed in lung; but not in placental stem villi vessels or cultured placental villi smooth muscle cells.
Post Translational ModificationNA
FunctionEndothelins are endothelium-derived vasoconstrictor peptides.
Length178
Molecular Weight19
NameEndothelin-2 (ET-2) (Preproendothelin-2) (PPET2)
SequenceCSCSSWLDKECVYFCHLDIIW
Sequence map21
PDB IDNA
DrugpediaNA
ReceptorP25101; P24530
DomainNA
Pharmaceutical UseNA