Detailed description page of Hmrbase2

This page displays user query in tabular form.

11806 details
Primary information
ID11806
Uniprot IDP0DKY6
DescriptionNatriuretic peptide NP2 (NP2_Casca)
OrganismCrotalus durissus cascavella
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Lepidosauria (lepidosaurs); Squamata (squamates); Bifurcata (split-tongued squamates); Unidentata; Episquamata; Toxicofera; Serpentes (snakes); Colubroidea; Viperidae; Crotalinae (pit vipers); Crotalus; Crotalus durissus (tropical rattlesnake); Cro
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the natriuretic peptide family.
Tissue SpecificityExpressed by the venom gland.
Post Translational ModificationNA
FunctionSnake venom natriuretic peptide that shows an increase in perfusion pressure; urinary flow and glomerular filtration rate. Reduces total and proximal tubular transport of sodium. In the aortic ring assay; causes a relaxant effect in endothelium-intact thoracic aortic rings precontracted with phenylephrine in the presence and absence of isatin; a natriuretic receptor antagonist.
Length33
Molecular Weight3
NameNatriuretic peptide NP2 (NP2_Casca)
SequenceVSTSRGSQGCFGLKLDRIGAASGLGCWRRIVDS
Sequence map33
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA