Detailed description page of Hmrbase2

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11800 details
Primary information
ID11800
Uniprot IDQ9N0T2
DescriptionCalcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I)
OrganismEquus caballus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Perissodactyla (odd-toed ungulates); Equidae (horses); Equus; Equus; Equus caballus (Horse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the calcitonin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionCGRP induces vasodilation. It dilates a variety of vessels including the coronary; cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
Length127
Molecular Weight13
NameCalcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I)
SequenceSCNTASCLTHRLAGLLSSAGSMANSNLLPTEMGFKVS
Sequence map37
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA