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11792 details
Primary information
ID11792
Uniprot IDQ99LS0
DescriptionAugurin (Esophageal cancer-related gene 4 protein homolog)
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageAt embryonic stage 14.5 dpc; primarily expressed in the choroid plexus; and low expression in the heart and cartilage (at protein level) (PubMed-21349154). At 18.5 dpc; expressed in adrenal cortex; ch
SimilarityBelongs to the augurin family.
Tissue SpecificityExpressed in the intermediate lobe of pituitary; glomerular layer of adrenal cortex; choroid plexus and atrioventricular node of the heart (PubMed-17284679). Expressed in the brain with high expressio
Post Translational ModificationNA
FunctionProbable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system
Length148
Molecular Weight16
NameAugurin (Esophageal cancer-related gene 4 protein homolog)
SequenceQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDVNYWLNRNRNGHDYYGDYYQRHYDEDAAIGPH
Sequence map62
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA