| Primary information |
|---|
| ID | 11786 |
| Uniprot ID | P05623 |
| Description | Accessory gland-specific peptide 70A (Paragonial peptide B) (Sex peptide) (SP) |
| Organism | Drosophila melanogaster |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Eremoneura; Cyclorrhapha; Schizophora; Acalyptratae; Ephydroidea; Drosophilidae (pomace flies); Drosophilinae; Drosophilini; Drosophila (fruit flies); Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster (Fruit fly) |
| Subcellular Location | Secreted |
| Developmental Stage | No expression in females or embryos (PubMed-3135120; PubMed-20458515). Expression levels are highest in male adults with little to no expression until the late pupal stages (PubMed-3135120; PubMed-204 |
| Similarity | Belongs to the Drosophila sex peptide family. |
| Tissue Specificity | Main cells of the accessory glands of males (paragonial gland). |
| Post Translational Modification | Sperm-bound protein is cleaved to release an active C-terminal peptide. Gradual release from stored sperm may function to prolong PMR and enhance male reproductive success. |
| Function | Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila |
| Length | 55 |
| Molecular Weight | 6 |
| Name | Accessory gland-specific peptide 70A (Paragonial peptide B) (Sex peptide) (SP) |
| Sequence | WEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGRC |
| Sequence map | 36 |
| PDB ID | 2LAQ; |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|