| Primary information |
|---|
| ID | 11785 |
| Uniprot ID | Q8JFY4 |
| Description | Ghrelin (Ghrelin-21) |
| Organism | Anguilla japonica |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Elopocephalai; Elopocephala; Elopomorpha; Anguilliformes (true eels); Anguillidae (freshwater eels); Anguilla; Anguilla japonica (Japanese eel) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the motilin family. |
| Tissue Specificity | Highest levels in stomach and anterior intestine. Lower levels in posterior intestine; kidney and brain. Low levels in heart; head kidney and middle intestine. |
| Post Translational Modification | O-octanoylation or O-decanoylation is essential for activity. The O-decanoylated form ghrelin-21-C10 differs in the length of the carbon backbone of the carboxylic acid forming an ester bond with Ser- |
| Function | Ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect; induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. |
| Length | 111 |
| Molecular Weight | 12 |
| Name | Ghrelin (Ghrelin-21) |
| Sequence | GSSFLSPSQRPQGKDKKPPRV |
| Sequence map | 21 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|