Detailed description page of Hmrbase2

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11746 details
Primary information
ID11746
Uniprot IDQ9DFD6
DescriptionHepcidin (Fragment)
OrganismOncorhynchus mykiss
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Protacanthopterygii; Salmoniformes (salmons and trouts); Salmonidae (salmonids); Salmoninae (trouts; salmons & chars); Oncorhynchus; Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the hepcidin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionSeems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity.
Length61
Molecular Weight6
NameHepcidin (Fragment)
SequenceXSHLSLCRWCCNCCHNKGXGFCCKF
Sequence map25
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA