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11742 details
Primary information
ID11742
Uniprot IDP05487
DescriptionConopressin-S (Con-S) (Arg-conopressin S)
OrganismConus striatus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Caenogastropoda; Neogastropoda; Conoidea; Conidae (cone shells); Conus; Pionoconus; Conus striatus (Striated cone)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the vasopressin/oxytocin family.
Tissue SpecificityExpressed by the venom duct.
Post Translational ModificationNA
FunctionInteracts with high affinity with vasopressin V1b receptor (AVPR1B) (Ki=8.3 nM); although the displacement of specific [3H]vasopressin binding is incomplete (a 30-40% resistant component remained). Has weaker affinity binding for oxytocin receptor (OXTR) (Ki=175 nM); and V1a receptor (AVPR1A) (Ki=827 nM).
Length9
Molecular Weight1
NameConopressin-S (Con-S) (Arg-conopressin S)
SequenceCIIRNCPRG
Sequence map9
PDB IDNA
DrugpediaNA
ReceptorNA
DomainThe cysteine framework is C-C.
Pharmaceutical UseNA