| Primary information |
|---|
| ID | 11742 |
| Uniprot ID | P05487 |
| Description | Conopressin-S (Con-S) (Arg-conopressin S) |
| Organism | Conus striatus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Caenogastropoda; Neogastropoda; Conoidea; Conidae (cone shells); Conus; Pionoconus; Conus striatus (Striated cone) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the vasopressin/oxytocin family. |
| Tissue Specificity | Expressed by the venom duct. |
| Post Translational Modification | NA |
| Function | Interacts with high affinity with vasopressin V1b receptor (AVPR1B) (Ki=8.3 nM); although the displacement of specific [3H]vasopressin binding is incomplete (a 30-40% resistant component remained). Has weaker affinity binding for oxytocin receptor (OXTR) (Ki=175 nM); and V1a receptor (AVPR1A) (Ki=827 nM). |
| Length | 9 |
| Molecular Weight | 1 |
| Name | Conopressin-S (Con-S) (Arg-conopressin S) |
| Sequence | CIIRNCPRG |
| Sequence map | 9 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | The cysteine framework is C-C. |
| Pharmaceutical Use | NA
|