Detailed description page of Hmrbase2

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11715 details
Primary information
ID11715
Uniprot IDP82972
DescriptionNatriuretic peptide PNP
OrganismPseudocerastes persicus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Lepidosauria (lepidosaurs); Squamata (squamates); Bifurcata (split-tongued squamates); Unidentata; Episquamata; Toxicofera; Serpentes (snakes); Colubroidea; Viperidae; Viperinae (vipers); Pseudocerastes; Pseudocerastes persicus (Persian horned vipe
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the natriuretic peptide family.
Tissue SpecificityExpressed by the venom gland.
Post Translational ModificationNA
FunctionIncreases urine flow and decreases blood pressure when administered to rats by intravenous injection. Inhibits thrombin-induced platelet aggregation. Stimulates cGMP production via the natriuretic peptide receptor-A (NPR1).
Length37
Molecular Weight3
NameNatriuretic peptide PNP
SequenceGENEPPKKKAPDGCFGHKIDRIGSHSGLGCNKFKPGH
Sequence map37
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA