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11684 details
Primary information
ID11684
Uniprot IDO46166
DescriptionU1-agatoxin-Ta1a (U1-AGTX-Ta1a) (Insecticidal toxin 1) (TaITX-1)
OrganismEratigena agrestis
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Chelicerata; Arachnida; Araneae (spiders); Araneomorphae; Entelegynae; RTA clade; Agelenidae (funnel weavers); Eratigena; Eratigena agrestis (Hobo spider) (Tegenaria agrestis)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the helical arthropod-neuropeptide-derived (HAND) family.
Tissue SpecificityExpressed by the venom gland.
Post Translational ModificationNA
FunctionToxin that paralyzes insects. May have a direct effect on the insect central nervous system.
Length68
Molecular Weight7
NameU1-agatoxin-Ta1a (U1-AGTX-Ta1a) (Insecticidal toxin 1) (TaITX-1)
SequenceEPDEICRARMTHKEFNYKSNVCNGCGDQVAACEAECFRNDVYTACHEAQK
Sequence map50
PDB ID2KSL; 6URP
DrugpediaNA
ReceptorNA
DomainIs exclusively composed of 4 tightly packed alpha
Pharmaceutical UseNA