Detailed description page of Hmrbase2

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11580 details
Primary information
ID11580
Uniprot IDP52115
DescriptionRenin
OrganismOvis aries
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular LocationSecreted Membrane. Note=Associated to membranes via binding to ATP6AP2
Developmental StageNA
SimilarityBelongs to the peptidase A1 family.
Tissue SpecificityKidney
Post Translational ModificationNA
FunctionRenin is a highly specific endopeptidase; whose only known function is to generate angiotensin I from angiotensinogen in the plasma; initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
Length400
Molecular Weight44016
NameRenin
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA