Primary information |
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ID | 11580 |
Uniprot ID | P52115 |
Description | Renin |
Organism | Ovis aries |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular Location | Secreted Membrane. Note=Associated to membranes via binding to ATP6AP2 |
Developmental Stage | NA |
Similarity | Belongs to the peptidase A1 family. |
Tissue Specificity | Kidney |
Post Translational Modification | NA |
Function | Renin is a highly specific endopeptidase; whose only known function is to generate angiotensin I from angiotensinogen in the plasma; initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
Length | 400 |
Molecular Weight | 44016 |
Name | Renin |
Sequence | NA |
Sequence map | NA |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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