| Primary information |
|---|
| ID | 11579 |
| Uniprot ID | P08424 |
| Description | Renin |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular Location | Secreted Membrane. Note=Associated to membranes via binding to ATP6AP2 |
| Developmental Stage | NA |
| Similarity | Belongs to the peptidase A1 family. |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Renin is a highly specific endopeptidase; whose only known function is to generate angiotensin I from angiotensinogen in the plasma; initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Length | 402 |
| Molecular Weight | 44276 |
| Name | Renin |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | Q6AXS4 |
| Domain | NA |
| Pharmaceutical Use | NA
|