| Primary information |
|---|
| ID | 11575 |
| Uniprot ID | P00797 |
| Description | Renin |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted Membrane. Note=Associated to membranes via binding to ATP6AP2 |
| Developmental Stage | NA |
| Similarity | Belongs to the peptidase A1 family. |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Renin is a highly specific endopeptidase; whose only known function is to generate angiotensin I from angiotensinogen in the plasma; initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Length | 406 |
| Molecular Weight | 45057 |
| Name | Renin |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | 1BBS1BIL1BIM1HRN1RNE2BKS2BKT2FS42G1N2G1O2G1R2G1S2G1Y2G202G212G222G242G262G272I4Q2IKO2IKU2IL22REN2V0Z |
| Drugpedia | NA |
| Receptor | O75787;O75787 |
| Domain | NA |
| Pharmaceutical Use | NA
|